CSF Dynamics and Normal-pressure Hydrocephalus

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Pulsatility in CSF dynamics: pathophysiology of idiopathic normal pressure hydrocephalus.

BACKGROUND It is suggested that disturbed CSF dynamics are involved in the pathophysiology of idiopathic normal pressure hydrocephalus (INPH). The pulsatility curve describes the relationship between intracranial pressure (ICP) and the amplitude of cardiac related ICP pulsations. The position of baseline ICP on the curve provides information about the physiological state of the CSF dynamic syst...

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CSF spaces in idiopathic normal pressure hydrocephalus: morphology and volumetry.

PURPOSE Idiopathic normal pressure hydrocephalus (NPH) is an important cause of dementia in the elderly; however, idiopathic NPH is often difficult to differentiate from normal aging and vascular dementias in which brain atrophy with ventricular dilatation (hydrocephalus ex vacuo or central atrophy) is present. To elucidate the distinctive features of the distribution of CSF in idiopathic NPH, ...

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Reduction of ventricular size after shunting for normal pressure hydrocephalus related to CSF dynamics before shunting.

Reduction of ventricular size was determined by repeated computed tomography in 30 adult patients shunted for normal pressure hydrocephalus (NPH) and related to the pressure-volume index (PVI) and resistance to outflow of cerebrospinal fluid (Rcsf) measured before shunting. Rapid and marked reduction of ventricular size (n = 10) was associated with a significantly lower PVI than slow and modera...

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The relationship between CSF circulation and cerebrovascular pressure-reactivity in normal pressure hydrocephalus.

OBJECTIVE Previously, we documented association between CSF circulation and transcranial-Doppler derived autoregulation in non-shunted patients suffering from hydrocephalus. In the present study we sought to investigate the relationship between the resistance to CSF outflow and pressure-reactivity both in shunted and non-shunted NPH patients. MATERIAL AND METHODS Sixty-eight patients (47 non-...

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Normal pressure hydrocephalus.

Normal pressure hydrocephalus (NPH) is a reversible disorder characterized by gait impairment, subcortical dementia, and urinary urgency and incontinence associated with impaired cerebrospinal fluid circulation and ventriculomegaly. Treatment with shunt surgery is most likely to increase mobility, and may also improve dementia and urinary symptoms. An international, independent study group rece...

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ژورنال

عنوان ژورنال: Japanese Journal of Neurosurgery

سال: 2018

ISSN: 0917-950X,2187-3100

DOI: 10.7887/jcns.27.581